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KMID : 1023120150130040469
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Korean Journal of Aesthetic Society
2015 Volume.13 No. 4 p.469 ~ p.476
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Effects of Formulation Containing Garlic Extract on Functional Skin Care: Antioxidation and Inhibitive Activities of Collagenase, Elastase and Tyrosinase
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Kim Young-Suk
Jung Eun-Young
Koh Hye-Jung
Hong Yang-Hee
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Abstract
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We was to evaluate the physiological effects of formulation containing garlic extract on skin care. The total polyphenol (p<.001), flavonoid (p<.001) contents and 1,1-diphenyl?2-picrylhydrazyl (DPPH) (p<.001), 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) (p<.01) radicals scavenging activities and reducing power (p<.05) of the garlic formulation were significantly higher compared to those of the base formulation. The inhibition of collagenase (p<.05) of the garlic formulation were significantly higher compared to those of the base formulation. Specially, the base formulation inhibited slightly elastase activity whereas the garlic formulation had about 8-fold higher elastase inhibitory activity (p<.001). When the garlic extract was added to the formulation, the tyrosinase activity was decreased significantly (p<.05, p<.01, p<.001). In conclusion, the garlic formulation had high inhibitory activities for tyrosinase and elastase, thus suggesting that garlic may have beneficial properties as a material for cosmeceuticals.
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KEYWORD
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Garlic formulation, Antioxidant effects, Collagenase, Pancreatic elastase, Tyrosinase
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